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Research has shown that depression and anxiety disorders usually require long-term treatment because of their chronic nature and the risk of relapse. Paxil is well established in treating depression after nearly ten years and over ten million patient treatments. Recent studies suggest an increased risk of Paxil birth defects for pregnant women during their first trimester. You may not be able to take Paxil for as long as your doctor advises. Your mood or symptoms. It convenient to take Paxil with breakfast. Research has shown that depression and anxiety disorders could be linked to a chemical imbalance in the brain. Symptoms, such as muscle tension, irritability and disturbedsleep. This age group - where chronic depression can affect a large proportion of this population.