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Flagyl or Metronidazole is the effective modern antibiotic. Flagyl or Metronidazole is the effective modern antibiotic. Metronidazole antibiotic is marketed by Pfizer under the trade name Flagyl, and also by various generic manufacturers, who sell it at a cheaper price. It is not necessary to take this drug with food, unless an upset stomach occurs. Flagyl is known to cause cancer in laboratory animals and this drug should only be taken if absolutely necessary. It is important to maintain a constant level of Flagyl in the blood. Metronidazole is an antibiotic effective against anaerobic bacteria and certain parasites. A second infection may occur.