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Prednisone is the most commonly-prescribed oral corticosteroid. Prednisone may interact with estrogens and phenytoin. Water-based suspension contains Prednisolone used to treat various inflammatory and allergy conditions as well as other diseases. Corticosteroids, including prednisone, are commonly used to suppress the immune system to attack by micro-organisms, it should be noted that it is very different from another group of steroids, called anabolic steroids, which have gained notoriety because of their abuse by some athletes and body builders. Before the needed effect is achieved. Prednisone is inactive in the body.