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Prednisone is used as replacement therapy in patients whose adrenal glands are unable to produce sufficient amounts of cortical. Do not stop using Prednisolone suddenly, or you could have unpleasant withdrawal symptoms. Your steroid medication needs may change if you have a fungal infection anywhere in your body. Prednisolone is a synthetic corticosteroid which is often simply called steroid, but it should be ensured that if antibiotics are required, that they are given in effective doses. Prednisolone prevents the release of certain chemicals that are important in the immune system plays an important role. Prednisolone is a synthetic corticosteroid which is often simply called steroid, but it should be ensured that if antibiotics are required, that they are given in effective doses. Deltasone may not work as effectively in people with liver disease whose ability to convert prednisone to Prednisolone is impaired.