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Amlodipine is only part of a complete program of treatment that may also include diet, exercise, weight control, and other medications. Check with your doctor before you stop taking Amlodipine, as a slow reduction in the dose may be needed. If you experience headache, insomnia, nausea, diarrhea, or constipation. If you experience headache, insomnia, nausea, diarrhea, or constipation. If you have certain heart conditions or liver disease. In patients with severe coronary artery disease, Amlodipine can increase the frequency and severity of angina or actually cause a heart attack on rare occasions. Amlodipine is taken once daily and may be used alone or in combination with other drugs for high blood pressure, you must take Norvasc regularly for it to be effective. If you are over 65 years of age, you may be more likely to experience side effects from Norvasc.