Symptoms associated with an unfavorable mental state need to be excessive and chronic to be considered to have in fact the medical problem of a major depressive disorder, as stated by others. You begin to feel better, it is important to take Paxil with breakfast. Avoid drinking alcohol, which can increase some of the side effects of Paroxetine. Zoloft, Paxil, Luvox and Prozac are currently used by more than five million Americans.